Product Description
Aceclofenac, a anti-inflammatory drug, has been used in the treatment of rheumatoid arthritis and osteoarthritis. In order to decrease the gastric ulcerogenic effects, aceclofenac gels have been developed. This study was conducted to develop a gel formulation of aceclofenac using four types of gelling agents: carbopol, hydroxypropylmethylcellulose(HPMC), carboxymethylcellulose sodium (Na CMC) and sodium alginate. Effect of penetration enhancer (propylene glycol) on the release has been studied. The gels were evaluated for physical appearance, rheological behavior, drug release and stability. The drug release from all gelling agents through a standard cellophane membrane was evaluated using Keshary-Chien diffusion cell. All gels showed acceptable physical properties concerning color, homogeneity, consistency, spreadability and pH value. Among all the gel formulations, carbopol showed superior drug release than followed by Na CMC, HPMC and sodium alginate. Drug release decreased with increase in polymer concentration. Drug release was not linearly proportional with the concentration of penetration enhancer or co-solvents. Stability studies showed that the physical appearance, rheological properties, and drug release remained unchanged upon storage for two months at ambient conditions.
Potent Pain Relief CreamAceclofenac Gel provides swift relief by reducing inflammation and alleviating muscular and joint pain. Specifically formulated for external application, its effectiveness stems from its high purity and careful formulation, catering to acute and chronic pain management.
Safe and Simple ApplicationThis analgesic gel is intended for external use only, ensuring ease of application directly to the affected region. Its refined cream base allows for rapid absorption, making it ideal for localized treatment under the guidance of a healthcare provider.
Ideal for Various Medical SettingsManufactured to be distributed across India, Aceclofenac Gel supports doctors, pharmacies, and healthcare facilities in pain management. Its easy availability through reputed suppliers and distributors ensures that patients have prompt access to reliable pain relief solutions.
FAQ's of Aceclofenac Gel:
Q: How should Aceclofenac Gel be applied for maximum benefit?
A: Apply Aceclofenac Gel gently to the affected area as directed by your physician. Make sure the skin is clean and dry before use. Do not apply on open wounds, and wash hands thoroughly after application.
Q: What are the main uses and benefits of Aceclofenac Gel?
A: Aceclofenac Gel is primarily used to relieve pain and inflammation associated with musculoskeletal conditions such as sprains, strains, or arthritis. Its analgesic properties provide targeted pain relief and support faster recovery.
Q: When should Aceclofenac Gel be used for effective results?
A: Use Aceclofenac Gel at the dosage and frequency recommended by your doctor. It's typically applied during episodes of pain or inflammation for optimal effect. Do not exceed the prescribed duration of use without medical advice.
Q: Where should Aceclofenac Gel be stored to maintain its efficacy?
A: Store Aceclofenac Gel in a cool place, away from direct sunlight and heat. Proper storage ensures the gel maintains its 100% purity and therapeutic value throughout its shelf life.
Q: What process is involved in obtaining Aceclofenac Gel in India?
A: Aceclofenac Gel is available through various channels in India, including pharmacies supplied by dealers, distributors, manufacturers, and wholesalers. To purchase, consult your healthcare provider and acquire it from a licensed supplier.
Q: Is a prescription necessary for using Aceclofenac Gel, and what are the dosage guidelines?
A: Yes, Aceclofenac Gel should only be used as directed by a physician. Strictly adhere to the dosage guidelines provided by your healthcare professional to ensure safety and effectiveness.
Q: What precautions should be taken when using Aceclofenac Gel externally?
A: Avoid applying the gel to broken or irritated skin. If you experience any unusual skin reactions, discontinue use and seek medical advice. Always follow your doctor's instructions regarding application and duration.